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The following notes refer to the related species Ilex aquifolium which has been used in Traditional Herbal Medicine: Holly is little used in modern herbalism. The leaves are diaphoretic, expectorant, febrifuge and tonic. The berries are violently emetic and purgative.
https://pfaf.org https://pfaf.org/user/Plant.aspx?LatinName=Ilex+aquifolium