Antiseptic, diuretic, and for smallpox in North American tradition

Moerman, D (1978) Field Guide to the Medicinal Plants of North America

Diphylleia cymosa is a synonym

http://www.plantsoftheworldonline.org/

Highly toxic if ingested or the skin is contaminated causing severe vomiting and brain damage. It is genotoxic.

Professor Anthony Dayan, 2022

"Humans/Pets: Harmful if eaten"- HTA guidelines

HTA Guide to Potentially Harmful Plants, 3rd Edition (2022)

Northern America, Southeastern U.S.A.